We are looking for talented, creative scientists with background in mass spectrometry, proteomics, structural biology or software development. Our work is focused on advancing integrative methods in structural biology using mass spectrometry, designed to extend accurate protein modeling to the interactome. These activities take place in a strongly thematic environment, involving structure-function problems in mitotic regulation and DNA damage repair.
We have an immediate need for individuals for the following funded projects:
Next-generation HX-MS systems. This project will develop and build new functionality for extending HX to ultracomplex states (NSERC CRD, Sciex).
Advanced MS software for higher order structure analysis. This project will extend our Mass Spec Studio framework into new applications relevant to research and biopharmaceuticals characterization (Cultivated Code Inc., NSERC I2I).
Novel strategies in bioconjugation. This project explores the use of photochemistries for high information-content protein footprinting (NSERC DG, UofC).
Integrative structural modeling. the project involves the development of novel strategies for merging MS-measured restraints with other sources of structural data (NSERC DG, UofC).
For more information on these opportunities, please contact:
Prof. David C. Schriemer
Dept. of Biochemistry & Molecular Biology, Faculty of Medicine
University of Calgary
Ph: (403) 210-3811